Experienced scientists working on antigen and antibody production, antibody engineering, lentivirus, and cell line development services for decades. >90% success rate of stable cell line generation.
Fast turnaround:
Antigen (peptide or protein) production: 3-6 weeks.
Mouse monoclonal antibody production: 20-24 weeks.
Screening phage or yeast libraries for fully human antibodies: 8-12 weeks.
Sequencing hybrioma antibody: 1-3 weeks.
Chimeric antibody production: 3-4 weeks.
Antibody humanization: 8-10 weeks.
Construction of CAR cassette, lentivirus packaging and production: 4-5 weeks.
T-cell activation, transduction, and CAR T-cell expansion: 4-5 weeks.
Confirmation of CAR expression, IFN-gamma ELISA, and cytotoxicity assay of transduced and expanded T-cells: 2 weeks.- Any gene;
- Any host cell, including primary cell;
- Highly efficient and precise.
Fast turnaround:
Knock-out cell line generation: 16-19 weeks.
Knock-in cell line generation: 20-24 weeks.Experienced scientists working on antibody and cell line development services for decades. >90% success rate of stable cell line generation.
Stable cell lines developed with our proprietary recombinant antibody expression system with multiple selectable markers is very productive in expressing target proteins.
Fast turnaround:
Basic service: 7-8 weeks.
Premium service: 12-14 weeks.
Pool cells: 6 weeks.Experienced scientists working on protein engineering, expression, and purification, and cell line development services for decades. >90% success rate of stable cell line generation.
Stable cell lines developed with our proprietary protein expression system with multiple selectable markers is very productive in expressing target proteins.
Fast turnaround:
1 week for synthesizing a gene for expressing the target protein.
1 week for molecular construction of the gene.
5-6 weeks for generation of suspension CHO stable cell lines expressing the target protein.
5-6 weeks for additional services included in the premium package.Our complete custom lentivirus production services include: 1) lentivirus vector construction for expression or silencing of a gene; 2) lentivirus packaging; 3) lentivirus purification; 4) lentivirus titering.
We have always optimized our lentivirus production systems, including lentivirus plasmid construction and low endotoxin plasmid preparation, host cells for lentivirus packaging, cell culture medium and lentivirus packaging process, small and large scale lentivirus purification process.
Fast turnaround: 2-3 weeks.Biologics production stable cell line development services utilize advanced technology platforms to generate cell lines expressing the target gene at very high levels for the manufacturing of recombinant proteins and antibodies.
- Performed under GLP; manufactured product may be used in FDA Nonclinical Laboratory Studies.
- Parental cell line is cGMP banked with certification.
- Set licensing fee arrangement for commercial production license.
- Cell lineage history of the cell line and testing details facilitate IND filing.While the success rate of stable cell line generation is highly dependent on the target genes and Syd Labs can not guarantee 100% success rate, our in-house data show a success rate greater than 90%.
Fast turnaround of stable cell line development: 6-7 weeks.
We have a lot of experience in dealing with difficult-to-express proteins.Syd Labs determines the titer of lentiviruses and retroviruses (provided by customer or produced by Syd Labs) using HT1080 cells.
Fast return: 2 weeks.